科研捷报｜2026 年第三季度新芝生物论文奖励结果公示

硕果盈枝，捷报频传！新芝生物2026年第三季度科研论文奖励公示如约而至。本季度入选论文聚焦三大热点领域：环境微生物修复、前药纳米递送、结构生物学。新芝明星仪器矩阵——MGC-500、SCIENTZ-IID、SCIENTZ-10N/A 再次成为科研攻关的“幕后功臣”。

截止目前，新芝仪器已累计助力多篇SCI论文见刊于 JHM、AHM、PNAS 等高分期刊，深度赋能微生物表征、纳米药物制备及天然产物活性保存全链路。

以下为本季度奖励概况及精选文献分享：

2026年新芝生物第三季度科研奖励公示表

B类：5篇（指定产品2篇）| C类：1篇 | D：类1篇

论文分享

以下展示3篇代表性论文

01

MGC-500 解码耐热芽孢杆菌汞胁迫生长曲线

《AI-2 type quorum-sensing signal 

enhances mercury resistance and 

adsorption in thermotolerant Bacillus 

subtilis》

【原文应用】

Bacterial growth under various temperatures and Hg concentrations S. Han et al. Journal of Hazardous Materials 515 (2026) 143148 2 was monitored via the changes in optical density at 600 nm (OD600) using an automated microbial growth curve analyzer (MGC? 500,  Ningbo Scientz Biotechnology Co., Ltd., Ningbo, China). Bacterial cells were disrupted using a Scientz-IID ultrasonic homogenizer (Ningbo Scientz Biotechnology Co., Ltd., Ningbo, China) to obtain a homogeneous suspension. Following ultrasonic cell disruption, the activities of antioxidant enzymes, in B. subtilis G4 were determined using commercial assay kits.

微生物生长曲线分析仪MGC-500

【应用价值】

MGC-500实现“温度×汞浓度”复合胁迫下的连续OD600自动采集，为耐热菌生长曲线、存活率判定提供无人工干预的高重复性数据，降低取样污染风险。

【设备优势提炼】

• 支持好氧、兼性厌氧、严格厌氧等微生物培养；

• 支持12孔、24孔、48孔和96孔微孔板的高通量培养；

• 可以实现300-850nm波长范围内全光谱扫描；

• 自动生成生长动力学曲线，支撑胁迫响应建模。

02

SCIENTZ-IID 协助释放前药纳米粒胞内信号

《Covalent “Locking” of Prodrug 

Nanoassemblies via Thiol-Ene Click 

Crosslinking for Potent Antitumor 

Therapy》

【原文应用】

4T1 cells were seeded in 12-well plates (1 × 105 cells/well) andcultured for 24 h. Subsequently, cells were treated with coumarin-6-labeled nanoassemblies (equivalent to 250 ng/mL coumarin-6) and incubated for 2, 4, or 8 h. At the predetermined time, the cells were dispersed in deionized water after a gentle wash with cold PBS. Subsequently, the cells were lysed using probe sonication (SCIENTZ-IID, Scientz Biotechnology Co., Ltd., Ningbo, China), and then centrifuged with the addition of acetonitrile to get supernatant, which contained intracellular drug. The fluorescence intensity was determined at 444 nm (excitation wavelength) and 505 nm (emission wavelength) via a microplate reader. The cell number was assessed by measuring the total protein concentration using a BCA assay kit.

超声波细胞粉碎机SCIENTZ-IID

【应用价值】

SCIENTZ-IID 超声波细胞粉碎机用于 4T1 肿瘤细胞的高效破碎与内容物释放，为后续细胞内纳米粒摄取量及药物浓度的精准定量提供了可靠的前处理保障。

【设备优势提炼】

• 探头式超声，破碎效率高；

• 可自定义编程多段超声程序组合；

• 超声时间，功率连续可调；

• 具有100μl-1200ml的破碎量。

03

SCIENTZ-10N/A 守护RiPP天然产物活性

《An N-acetylated daropeptide modulates nematode development》

【原文应用】

For production and purification of aphotorhaptinA, the E. coli BL21 (DE3) cells coexpressing PasABC were harvested via centrifugation and the cell pellets were resuspended in 80% MeCN (a.q., 20 mL per L culture cells).The cells were then disrupted via sonication and the resulting cell lysate was subjected to rotary evaporation to remove organic solvent, lyophilized to dryness by a freeze dryer (SCIENTZ-10N/A, Ningbo Scientz Biotechnology Co.,Ltd.,Ningbo,China), and then purified by HPLC via a procedure detailed in SI Appendix.

普通型冻干机SCIENTZ-10N/A

【应用价值】

SCIENTZ-10N/A 完成异源表达菌裂解液低温冻干，避免有机溶剂残留对 aphotorhaptin A 结构与后续 NMR 解析的干扰。

【设备优势提炼】

• 科研级冻干曲线，蛋白/多肽活性保留率高；

• 可配置充气阀，可充干燥惰性气体；

• 可设定冷阱温度，低于温度设定值时开启真空泵

• 适用于小型实验室，并可选择多种配置。

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